Variations in the blood pressure response to repeated administration of tetraethyl ammonium chloride.
نویسندگان
چکیده
منابع مشابه
Sympathetic activity in cerebral embolism.
(3) Hypertension produced by vertebral embolism disappeared on administration of hexamethonium or tetraethyl-ammonium chloride immediately after the rise of blood pressure, whereas it became more marked following the administration of the latter after several minutes indicating increased circulating vasopressor substances. After administration of either hexamethonium or phenoxybenzamine, verteb...
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Since the introduction of tetraethyl ammonium as a ganglionic blocking agent, it has been used in the experimental induction of postural hypotension,’ as a diagnostic aid in pheochromocytoma,2 and, tentatively, In bronchial asthma and left ventricular failure.3’4 Not only is the arterial blood pressure lowered, but the venous,5 the pulmonary arterial,6 and the pulmonary “capillary bed”7 pressur...
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Probably the first studies of the pharmacology of quaternary ammonium compounds were made by Crum-Brown and Fraser in 1868. Burn and Dale (1915) found that, unlike nicotine, tetraethyl-ammonium chloride blocked autonomic ganglia without noticeable initial stimulation. Barlow and Ing (1948a and b), Paton and Zaimis (1948a and b), and Balaban et al. (1949) studied the properties of some chemical ...
متن کاملStudies on acute and chronic toxicity of tetraethyl ammonium ion (etamon); methods of reviving dogs after a lethal dose.
Studies were done using dogs to determine: (1) the EDoo* of Etamon when given as an infusion over 30 minutes; (2) the possibility of an accumulative toxicity when Etamon is given in multiple small doses over long periods of time; and (3) the effect of various measures in preventing death after the administration of a lethal dose (LDloo*) of Etamon. The ED,0 of Etamon given as an infusion was fo...
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Introduction: The underlying mechanism responsible for the cardiovascular response to hemorrhage (HEM) is still unknown; however, several brain areas, such as the cuneiform nucleus (CnF) have shown to be involved. In this study, the cardiovascular effect of the CnF during HEM was evaluated. Methods: The animals were divided into the following groups: 1. Vehicle; 2. HEM; 3. Cobalt chloride (CoC...
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ورودعنوان ژورنال:
- The Journal of clinical investigation
دوره 27 1 شماره
صفحات -
تاریخ انتشار 1948